Across TCGA cell cohorts, QTRT1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible QTRT1-associated genes across cancer lineages are PTH, ENPP6, and USP17L4. Each is linked with QTRT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both QTRT1-to-partner and partner-to-QTRT1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (QTRT1→partner) and Y-score (partner→QTRT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PTH →	+0.049	+3.684	<.001	.006	3	1
LARGE_INTESTINE	ENPP6 →	+0.038	+3.793	.002	.007	3	1
LARGE_INTESTINE	USP17L4 →	+0.012	+4.217	.005	.001	3	1
LUNG_NSCLC_LUAD	CCDC42 →	+0.054	+4.273	.008	.006	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

QTRT1 survival (RNA) · tumor vs normal (RNA) · all QTRT1 data types