QSOX2

Across TCGA patient cohorts, QSOX2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,855 significant associations in total. GBM shows the largest number of these associations.

The most reproducible QSOX2-associated genes across cancer lineages are TOR1B, MPP7, and ERBB4. Each is linked with QSOX2 in more than 3 cancer types. Because this analysis shows association rather than direction, both QSOX2-to-partner and partner-to-QSOX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, QSOX2 versus TOR1B in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (QSOX2→partner) and Y-score (partner→QSOX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TOR1B →	+0.452	+0.322	<.001	.002	3	4
BRCA	MPP7 →	-1.260	-0.411	<.001	.001	3	4
BRCA	ERBB4 →	-1.816	-0.373	<.001	.001	3	4
LSCC	RPL39P16 →	+0.835	+0.338	<.001	<.001	3	4
BRCA	ZMAT1 →	-0.874	-0.383	<.001	<.001	3	4
OV	CALHM2 →	-0.759	-0.337	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,855 associations by consensus.

QSOX2 vs TOR1B — OV

Explore this scatter interactively →