QSOX2

Across TCGA cell cohorts, QSOX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,236 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible QSOX2-associated GO terms across cancer lineages are Transcription by RNA polymerase I, Transcription initiation at RNA polymerase I promoter, and Transcription by RNA polymerase III. Each is linked with QSOX2 in more than 14 cancer types. Because this analysis shows association rather than direction, both QSOX2-to-partner and partner-to-QSOX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription by RNA polymerase I grouped by QSOX2-low versus QSOX2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (QSOX2→partner) and Y-score (partner→QSOX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Transcription by RNA polymerase I →	+0.138	+1.082	.001	.007	3	15
BONE	Transcription initiation at RNA polymerase I promoter →	+0.119	+0.954	.001	.001	3	15
LARGE_INTESTINE	Transcription by RNA polymerase III →	+0.075	+0.920	<.001	<.001	3	15
SOFT_TISSUE	Establishment of mitotic spindle localization →	+0.142	+0.960	<.001	<.001	3	13
BONE	Metaphase/anaphase transition of cell cycle →	+0.177	+0.808	<.001	<.001	3	13
STOMACH	Nuclear transport →	+0.089	+1.078	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,236 associations by consensus.

Transcription by RNA polymerase I by QSOX2 expression — OESOPHAGUS

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