QSER1

Across TCGA patient cohorts, QSER1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,152 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible QSER1-associated genes across cancer lineages are VRK1, GINS1, and MYBL2. Each is linked with QSER1 in more than 5 cancer types. Because this analysis shows association rather than direction, both QSER1-to-partner and partner-to-QSER1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, QSER1 versus VRK1 in HNSC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (QSER1→partner) and Y-score (partner→QSER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	VRK1 →	+0.755	+0.257	<.001	.001	3	6
LSCC	GINS1 →	+0.747	+0.308	<.001	<.001	3	6
UCEC	MYBL2 →	+1.862	+0.386	<.001	<.001	3	6
UCEC	FAM83D →	+1.465	+0.275	<.001	<.001	3	6
UCEC	SUV39H1 →	+0.580	+0.235	<.001	.007	3	6
UCEC	CENPI →	+1.072	+0.327	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,152 associations by consensus.

QSER1 vs VRK1 — HNSC

Explore this scatter interactively →