QRSL1P3

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, QRSL1P3 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated QRSL1P3 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher QRSL1P3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated QRSL1P3 expression acts as an unfavorable survival marker, although some lineages such as LUAD and GBM show a favorable association.

UVM, COAD, and LUAD are the cancer types where QRSL1P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMOSTertileAll0.3440.788<.00187view →
COADDFSMedianIII,IV0.5710.744.00183view →
LUADDFSQuartileII,III,IV0.7950.596.00250view →
LGGOSQuartileAll0.7310.858<.00136view →
LUSCDFSQuartileIII,IV0.1780.762.00621view →
ACCOSTertileIV0.3270.633.04518view →
THCADFSTertileIV0.4550.952.00117view →
GBMOSQuartileAll0.5590.349.00213view →
KIRCOSTertileAll0.5350.694.01312view →
UCSDFSQuartileIII,IV0.1550.470.00612view →
THYMOSTertileAll1.0000.674.01411view →
UCECDFSQuartileII,III,IV0.6280.762.03310view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

QRSL1P3–UVM (OS)

Kaplan–Meier survival curve for QRSL1P3 RNA-high vs -low samples in UVM.

Open the UVM breakdown →

Exploration