QRSL1

Across TCGA cell cohorts, QRSL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,499 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible QRSL1-associated GO terms across cancer lineages are Glutaminyl-tRNAGln biosynthesis via transamidation, Mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication, and Nuclear transport. Each is linked with QRSL1 in more than 18 cancer types. Because this analysis shows association rather than direction, both QRSL1-to-partner and partner-to-QRSL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glutaminyl-tRNAGln biosynthesis via transamidation grouped by QRSL1-low versus QRSL1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (QRSL1→partner) and Y-score (partner→QRSL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Glutaminyl-tRNAGln biosynthesis via transamidation →	+0.101	+1.234	<.001	<.001	3	19
LIVER	Mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication →	+0.114	+0.600	.007	.001	2	16
UPPER_AERODIGESTIVE_TRACT	Nuclear transport →	+0.070	+0.873	.002	<.001	3	14
PANCREAS	Spermine biosynthetic process →	+0.135	+0.824	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication maintenance of fidelity →	+0.091	+0.687	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Nucleocytoplasmic transport →	+0.070	+0.905	.002	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,499 associations by consensus.

Glutaminyl-tRNAGln biosynthesis via transamidation by QRSL1 expression — BLOOD_Lymphoma

Explore this box plot interactively →