QRICH2

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, QRICH2 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated QRICH2 data layer compared with 24 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher QRICH2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated QRICH2 expression acts as an unfavorable survival marker.

PDAC are the cancer types where QRICH2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PDACDFSMedianII,III,IV0.5961.000.0229view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

QRICH2–PDAC (DFS)

Kaplan–Meier survival curve for QRICH2 mass-spec protein-high vs -low samples in PDAC.

Open the PDAC breakdown →

Exploration