QRICH2

Across TCGA cell cohorts, QRICH2 mutation is significantly associated with the RNA expression of many other genes, with 526 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible QRICH2-associated genes across cancer lineages are TEX26, ZIC5, and GATAD2B. Each is linked with QRICH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both QRICH2-to-partner and partner-to-QRICH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX26 grouped by QRICH2-low versus QRICH2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (QRICH2→partner) and Y-score (partner→QRICH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TEX26 →	+0.014	+3.452	.002	.004	3	2
BLOOD_Leukemia	ZIC5 →	+0.517	+3.375	<.001	.005	3	2
BLOOD_Leukemia	GATAD2B →	+0.620	+3.120	.005	.009	3	2
BLOOD_Leukemia	SNTG2 →	+0.823	+3.328	.003	.009	3	2
BLOOD_Leukemia	GPR151 →	+0.037	+3.853	<.001	.002	3	2
UPPER_AERODIGESTIVE_TRACT	MINAR2 →	+0.066	+4.736	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 526 associations by consensus.

TEX26 by QRICH2 expression — BLOOD_Lymphoma

Explore this box plot interactively →