Across TCGA pan-cancer cohorts, QRICH1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated QRICH1 data layer compared with 22 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher QRICH1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated QRICH1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

UCEC, LUAD, and CCRCC are the cancer types where QRICH1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	II,III,IV	0.567	1.000	.004	30	view →
LUAD	DFS	Median	All	0.759	0.479	.001	20	view →
CCRCC	DFS	Quartile	II,III,IV	0.833	0.398	.013	10	view →
PDAC	DFS	Median	III,IV	0.190	0.486	.036	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: QRICH1 tumor-vs-normal RNA expression · all QRICH1 data types