Across TCGA patient cohorts, QRICH1 mutation is significantly associated with the RNA expression of many other genes, with 1,741 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible QRICH1-associated genes across cancer lineages are CENPU, BAG1, and NDUFA6. Each is linked with QRICH1 in more than 2 cancer types. Because this analysis shows association rather than direction, both QRICH1-to-partner and partner-to-QRICH1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (QRICH1→partner) and Y-score (partner→QRICH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPU →	+0.589	+1.684	.002	.003	3	3
UCEC	BAG1 →	+0.587	+3.403	<.001	<.001	3	3
UCEC	NDUFA6 →	+0.436	+2.295	<.001	<.001	3	3
UCEC	TAF9 →	+0.504	+1.938	<.001	.001	3	2
UCEC	CCL4 →	+0.726	+2.284	.001	<.001	3	2
UCEC	SRCIN1 →	-0.592	-2.406	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,741 associations by consensus.

Exploration

QRICH1 survival (RNA) · tumor vs normal (RNA) · all QRICH1 data types