Across TCGA patient cohorts, QRICH1 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible QRICH1-associated genes across cancer lineages are PDCD4, MEK1, and Stathmin. Each is linked with QRICH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both QRICH1-to-partner and partner-to-QRICH1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (QRICH1→partner) and Y-score (partner→QRICH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PDCD4 →	-0.555	-2.991	.011	.036	3	2
UCEC	MEK1 →	+0.321	+1.736	.011	.007	3	2
UCEC	Stathmin →	+0.117	+1.440	.013	.024	3	2
UCEC	ATM →	-0.398	-1.687	.011	.040	3	2
COAD	Bcl-2 →	+0.422	+3.008	.003	.019	3	1
COAD	E-Cadherin →	-0.700	-2.991	.033	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Exploration

QRICH1 survival (RNA) · tumor vs normal (RNA) · all QRICH1 data types