Across TCGA cell cohorts, QRICH1 mutation is significantly associated with the mutation status of many other genes, with 3,561 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible QRICH1-associated genes across cancer lineages are PCDHA9, OR14J1, and EPS8L3. Each is linked with QRICH1 in more than 3 cancer types. Because this analysis shows association rather than direction, both QRICH1-to-partner and partner-to-QRICH1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (QRICH1→partner) and Y-score (partner→QRICH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PCDHA9 →	+4.429	+5.247	.005	.005	1	4
LUNG_NSCLC_LUAD	OR14J1 →	+5.000	+4.187	.008	.008	1	3
SKIN	EPS8L3 →	+2.977	+4.392	.005	.005	1	3
SKIN	ERCC6 →	+4.392	+4.392	.009	.009	1	3
LARGE_INTESTINE	ZNF536 →	+1.478	+3.408	.007	.007	1	3
LARGE_INTESTINE	ZSWIM8 →	+2.992	+4.767	<.001	<.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,561 associations by consensus.

Exploration

QRICH1 survival (RNA) · tumor vs normal (RNA) · all QRICH1 data types