Across TCGA pan-cancer cohorts, QRFPR Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated QRFPR data layer compared with 23 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher QRFPR Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated QRFPR expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

HNSC, READ, and UCEC are the cancer types where QRFPR Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.152	0.768	<.001	24	view →
READ	OS	Median	II,III,IV	0.187	0.653	.030	6	view →
UCEC	DFS	Median	II,III,IV	1.000	0.489	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: QRFPR tumor-vs-normal RNA expression · all QRFPR data types