Across TCGA patient cohorts, QRFPR mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible QRFPR-associated genes across cancer lineages are eIF4E, INPP4B, and Notch1. Each is linked with QRFPR in more than 1 cancer types. Because this analysis shows association rather than direction, both QRFPR-to-partner and partner-to-QRFPR results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (QRFPR→partner) and Y-score (partner→QRFPR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.162	+2.335	.033	.018	3	2
UCEC	INPP4B →	-0.349	-2.415	.002	.003	3	2
UCEC	Notch1 →	+0.118	+2.232	.020	.005	3	2
UCEC	Caspase-7-cleavedD198 →	+0.572	+2.341	.007	.003	3	2
UCEC	14-3-3_beta →	-0.081	-2.295	.024	.033	3	1
UCEC	EGFR_pY1068 →	-0.234	-2.459	.009	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration

QRFPR survival (RNA) · tumor vs normal (RNA) · all QRFPR data types