QPRT

Across TCGA patient cohorts, QPRT RNA expression is significantly associated with the protein abundance of many other proteins, with 11,005 significant associations in total. GBM shows the largest number of these associations.

The most reproducible QPRT-associated proteins across cancer lineages are WFS1, ACSF2, and CSNK1A1_S313. Each is linked with QPRT in more than 4 cancer types. Because this analysis shows association rather than direction, both QPRT-to-partner and partner-to-QPRT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, QPRT versus WFS1 in GBM, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (QPRT→partner) and Y-score (partner→QPRT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WFS1 →	+0.427	+0.701	<.001	.001	3	5
UCEC	ACSF2 →	+0.654	+1.002	<.001	<.001	3	5
LSCC	CSNK1A1_S313 →	-0.964	-1.391	<.001	<.001	3	4
GBM	CUL7 →	+0.372	+0.722	<.001	.006	3	4
LSCC	CLDN3 →	+1.238	+1.124	<.001	<.001	3	4
GBM	TPD52L2 →	+0.298	+0.920	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,005 associations by consensus.

QPRT vs WFS1 — GBM

Explore this scatter interactively →