QPRT

Across TCGA patient cohorts, QPRT mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible QPRT-associated genes across cancer lineages are CD8+ T-cells, Pericytes, and Adipocytes. Each is linked with QPRT in more than 1 cancer types. Because this analysis shows association rather than direction, both QPRT-to-partner and partner-to-QPRT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by QPRT-low versus QPRT-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (QPRT→partner) and Y-score (partner→QPRT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	CD8+ T-cells →	+0.031	+5.177	.005	.007	3	1
BLCA	Pericytes →	+0.078	+4.173	<.001	.027	3	1
UCEC	Adipocytes →	+0.023	+2.144	.018	.036	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD8+ T-cells by QPRT expression — BLCA

Explore this box plot interactively →