QPCT

Across TCGA pan-cancer cohorts, QPCT mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated QPCT data layer compared with 27 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher QPCT mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated QPCT expression acts as an unfavorable survival marker, although some lineages such as UCEC and CCRCC show a favorable association.

UCEC, LUAD, and CCRCC are the cancer types where QPCT mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.952	0.768	.005	26	view →
LUAD	DFS	Quartile	III,IV	0.509	0.996	.008	15	view →
CCRCC	OS	Median	IV	0.785	0.123	.009	11	view →
OV	DFS	Median	All	1.000	0.603	.005	4	view →
HNSC	OS	Tertile	II,III,IV	0.809	0.604	.023	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

QPCT–UCEC (DFS)

Open the UCEC breakdown →