QPCT

Across TCGA patient cohorts, QPCT protein abundance is significantly associated with the RNA expression of many other genes, with 7,546 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible QPCT-associated genes across cancer lineages are FCGR3B, CXCR1, and FCAR. Each is linked with QPCT in more than 4 cancer types. Because this analysis shows association rather than direction, both QPCT-to-partner and partner-to-QPCT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, QPCT versus FCGR3B in LSCC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (QPCT→partner) and Y-score (partner→QPCT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FCGR3B →	+1.244	+0.503	<.001	<.001	3	5
LSCC	CXCR1 →	+1.097	+0.517	<.001	<.001	3	5
GBM	FCAR →	+0.802	+0.456	<.001	<.001	3	5
LSCC	CEACAM3 →	+0.632	+0.453	<.001	<.001	3	4
LSCC	CXCR2 →	+0.996	+0.475	<.001	<.001	3	4
HNSC	CSF3 →	+0.989	+0.343	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,546 associations by consensus.

QPCT vs FCGR3B — LSCC

Explore this scatter interactively →