QPCT

Across TCGA cell cohorts, QPCT RNA expression is significantly associated with the go_rna of many other GO terms, with 4,353 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible QPCT-associated GO terms across cancer lineages are Microglia development, Mitochondrial electron transport, cytochrome c to oxygen, and Positive regulation of matrix metallopeptidase secretion. Each is linked with QPCT in more than 7 cancer types. Because this analysis shows association rather than direction, both QPCT-to-partner and partner-to-QPCT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microglia development grouped by QPCT-low versus QPCT-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (QPCT→partner) and Y-score (partner→QPCT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Microglia development →	-0.725	-1.373	<.001	.003	3	8
LUNG_SCLC	Mitochondrial electron transport, cytochrome c to oxygen →	+0.093	+3.663	.001	<.001	3	8
BLOOD_Lymphoma	Positive regulation of matrix metallopeptidase secretion →	-0.139	-1.191	<.001	<.001	3	7
STOMACH	Positive regulation of intracellular transport →	+0.086	+2.335	<.001	<.001	3	7
BLOOD_Leukemia	Endosome transport via multivesicular body sorting pathway →	+0.099	+0.892	<.001	<.001	3	7
BONE	Positive regulation of blood pressure by epinephrine-norepinephrine →	+0.538	+1.948	.002	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,353 associations by consensus.

Microglia development by QPCT expression — BLOOD_Lymphoma

Explore this box plot interactively →