QKI

Across TCGA pan-cancer cohorts, QKI Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated QKI data layer compared with 26 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher QKI Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated QKI expression acts as an unfavorable survival marker.

BLCA, UCEC, and GBM are the cancer types where QKI Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.165	0.620	<.001	30	view →
UCEC	OS	Median	IV	0.225	0.772	<.001	12	view →
GBM	OS	Median	All	0.020	0.416	<.001	6	view →
CHOL	OS	Median	All	0.155	0.725	.029	3	view →
READ	OS	Median	III,IV	0.328	0.750	.012	3	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →
PRAD	OS	Median	All	0.491	0.893	.002	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

QKI–BLCA (OS)

Open the BLCA breakdown →