QARS1

Across TCGA pan-cancer cohorts, QARS1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated QARS1 data layer compared with 23 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher QARS1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated QARS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

PDAC, HNSC, and LUAD are the cancer types where QARS1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	IV	0.214	0.785	.006	12	view →
HNSC	DFS	Tertile	IV	0.821	0.549	.030	4	view →
LUAD	OS	Median	III,IV	0.796	0.410	.035	4	view →
CCRCC	DFS	Quartile	All	0.893	0.620	.042	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

QARS1–PDAC (DFS)

Open the PDAC breakdown →