QARS1

Across TCGA cell cohorts, QARS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,720 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible QARS1-associated GO terms across cancer lineages are Arginyl-tRNA aminoacylation, Aminoacyl-tRNA metabolism involved in translational fidelity, and Positive regulation of G2/MI transition of meiotic cell cycle. Each is linked with QARS1 in more than 10 cancer types. Because this analysis shows association rather than direction, both QARS1-to-partner and partner-to-QARS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Arginyl-tRNA aminoacylation grouped by QARS1-low versus QARS1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (QARS1→partner) and Y-score (partner→QARS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Arginyl-tRNA aminoacylation →	+0.132	+0.681	<.001	<.001	3	11
BONE	Aminoacyl-tRNA metabolism involved in translational fidelity →	+0.088	+0.506	<.001	<.001	3	9
KIDNEY	Positive regulation of G2/MI transition of meiotic cell cycle →	+0.154	+0.824	.002	<.001	3	8
LARGE_INTESTINE	Amino acid metabolic process →	+0.060	+0.489	.006	.003	3	7
LUNG_SCLC	Mitochondrial tRNA 3'-end processing →	+0.095	+0.655	.002	<.001	3	7
KIDNEY	Positive regulation of meiotic cell cycle phase transition →	+0.114	+0.521	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,720 associations by consensus.

Arginyl-tRNA aminoacylation by QARS1 expression — BONE

Explore this box plot interactively →