PYY2

Across TCGA patient cohorts, PYY2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,231 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PYY2-associated proteins across cancer lineages are SUPT6H, TRIM24, and BPTF_S216. Each is linked with PYY2 in more than 4 cancer types. Because this analysis shows association rather than direction, both PYY2-to-partner and partner-to-PYY2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PYY2 versus SUPT6H in LSCC, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PYY2→partner) and Y-score (partner→PYY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SUPT6H →	+0.303	+1.369	<.001	<.001	3	5
GBM	TRIM24 →	+0.403	+0.524	.001	.001	3	4
LSCC	BPTF_S216 →	+0.315	+0.947	<.001	<.001	3	4
LSCC	DHX8 →	+0.372	+1.249	<.001	<.001	3	4
LUAD	ANP32E →	+0.486	+0.562	<.001	<.001	3	4
LSCC	NIPBL →	+0.247	+1.277	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,231 associations by consensus.

PYY2 vs SUPT6H — LSCC

Explore this scatter interactively →