PYROXD2

Across TCGA patient cohorts, PYROXD2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,314 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PYROXD2-associated genes across cancer lineages are ZNF507, ZNF566, and ZNF174. Each is linked with PYROXD2 in more than 3 cancer types. Because this analysis shows association rather than direction, both PYROXD2-to-partner and partner-to-PYROXD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PYROXD2 versus ZNF507 in OV, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PYROXD2→partner) and Y-score (partner→PYROXD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZNF507 →	-0.999	-0.688	.001	.003	3	4
OV	ZNF566 →	-0.583	-0.640	<.001	.002	3	4
OV	ZNF174 →	-0.414	-0.774	.004	.001	3	3
BRCA	NNT →	-0.554	-0.435	.004	.007	3	3
LSCC	POGK →	-0.581	-0.465	<.001	<.001	3	3
BRCA	CCDC15 →	-0.529	-0.494	.008	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,314 associations by consensus.

PYROXD2 vs ZNF507 — OV

Explore this scatter interactively →