PYROXD2

Across TCGA cell cohorts, PYROXD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,949 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PYROXD2-associated GO terms across cancer lineages are Cilium-dependent cell motility, Cilium or flagellum-dependent cell motility, and Cilium movement involved in cell motility. Each is linked with PYROXD2 in more than 11 cancer types. Because this analysis shows association rather than direction, both PYROXD2-to-partner and partner-to-PYROXD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium-dependent cell motility grouped by PYROXD2-low versus PYROXD2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PYROXD2→partner) and Y-score (partner→PYROXD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.086	-1.184	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.086	-1.184	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.089	-1.184	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.099	+1.448	.005	.001	3	11
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.093	+1.233	.002	<.001	3	11
OVARY	Regulation of intracellular transport →	+0.055	+1.057	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,949 associations by consensus.

Cilium-dependent cell motility by PYROXD2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →