PYM1

Across TCGA patient cohorts, PYM1 RNA expression is significantly associated with the RNA expression of many other genes, with 19,048 significant associations in total. ACC shows the largest number of these associations.

The most reproducible PYM1-associated genes across cancer lineages are ORMDL2, CHCHD1, and NOP10. Each is linked with PYM1 in more than 31 cancer types. Because this analysis shows association rather than direction, both PYM1-to-partner and partner-to-PYM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PYM1 versus ORMDL2 in ACC, with a Pearson correlation of 0.72.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PYM1→partner) and Y-score (partner→PYM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	ORMDL2 →	+0.763	+0.619	<.001	<.001	3	32
UVM	CHCHD1 →	+0.594	+0.596	<.001	<.001	3	31
ACC	NOP10 →	+0.874	+0.587	<.001	<.001	3	31
ACC	SNRPGP2 →	+0.958	+0.676	<.001	<.001	3	31
KICH	EXOSC1 →	+0.661	+0.447	.002	.002	3	31
ACC	IMP3 →	+0.854	+0.496	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,048 associations by consensus.

PYM1 vs ORMDL2 — ACC

Explore this scatter interactively →