PYM1

Across TCGA cell cohorts, PYM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,341 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible PYM1-associated GO terms across cancer lineages are GTP metabolic process, Regulation of plasminogen activation, and Bundle of His cell to Purkinje myocyte communication. Each is linked with PYM1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PYM1-to-partner and partner-to-PYM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GTP metabolic process grouped by PYM1-low versus PYM1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PYM1→partner) and Y-score (partner→PYM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	GTP metabolic process →	-0.081	-0.634	.003	.009	2	10
BREAST	Regulation of plasminogen activation →	-0.288	-1.194	<.001	<.001	3	9
URINARY_TRACT	Bundle of His cell to Purkinje myocyte communication →	+0.393	+0.607	.009	<.001	3	8
LUNG_NSCLC_LUSC	Luteinization →	-1.169	-0.592	.004	.001	2	9
SKIN	Positive regulation of keratinocyte differentiation →	+0.094	+0.379	.001	.006	3	8
LUNG_NSCLC_LUAD	Serotonin secretion →	+0.880	+0.468	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,341 associations by consensus.

GTP metabolic process by PYM1 expression — STOMACH

Explore this box plot interactively →