PYHIN1

Across TCGA cell cohorts, PYHIN1 RNA expression is significantly associated with the RNA expression of many other genes, with 2,193 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PYHIN1-associated genes across cancer lineages are CD52, IFI16, and SASH3. Each is linked with PYHIN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PYHIN1-to-partner and partner-to-PYHIN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PYHIN1 versus CD52 in BLOOD_Lymphoma, with a Pearson correlation of 0.46.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PYHIN1→partner) and Y-score (partner→PYHIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CD52 →	+4.268	+2.147	<.001	<.001	3	3
BLOOD_Lymphoma	IFI16 →	+2.088	+2.194	<.001	<.001	3	3
BLOOD_Myeloma	SASH3 →	+3.568	+0.098	<.001	.002	3	3
BLOOD_Leukemia	P2RY10 →	+1.802	+1.191	<.001	.003	3	3
BLOOD_Myeloma	RIC3 →	+2.682	+0.142	<.001	.001	3	2
BLOOD_Myeloma	NLRC3 →	+1.893	+0.158	<.001	.002	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,193 associations by consensus.

PYHIN1 vs CD52 — BLOOD_Lymphoma

Explore this scatter interactively →