PYDC2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PYDC2 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible PYDC2-associated genes across cancer lineages are MEP. Each is linked with PYDC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PYDC2-to-partner and partner-to-PYDC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEP grouped by PYDC2-low versus PYDC2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PYDC2→partner) and Y-score (partner→PYDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMMEP →+0.043+2.839.010.03511
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

MEP by PYDC2 expression — SKCM

Box plot of MEP in PYDC2-low vs PYDC2-high samples in SKCM.

Explore this box plot interactively →

Exploration