PXMP4

Across TCGA patient cohorts, PXMP4 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PXMP4-associated genes across cancer lineages are Monocytes, MEP, and Th1 cells. Each is linked with PXMP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PXMP4-to-partner and partner-to-PXMP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monocytes grouped by PXMP4-low versus PXMP4-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PXMP4→partner) and Y-score (partner→PXMP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	Monocytes →	+0.054	+5.305	<.001	.048	3	1
UCEC	MEP →	+0.030	+3.180	.045	.010	1	1
UCEC	Th1 cells →	+0.139	+3.169	.006	.020	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Monocytes by PXMP4 expression — LIHC

Explore this box plot interactively →