PXMP4

Across TCGA cell cohorts, PXMP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,153 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible PXMP4-associated GO terms across cancer lineages are Regulation of Golgi inheritance, Negative regulation of calcium ion export across plasma membrane, and Positive regulation of macrophage proliferation. Each is linked with PXMP4 in more than 11 cancer types. Because this analysis shows association rather than direction, both PXMP4-to-partner and partner-to-PXMP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of Golgi inheritance grouped by PXMP4-low versus PXMP4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PXMP4→partner) and Y-score (partner→PXMP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of Golgi inheritance →	+0.192	+1.022	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of calcium ion export across plasma membrane →	+0.080	+1.014	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Positive regulation of macrophage proliferation →	+0.239	+1.137	<.001	<.001	3	11
SKIN	Cytosolic transport →	+0.075	+1.032	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Protein-containing complex disassembly →	+0.076	+1.215	<.001	<.001	3	10
STOMACH	Caveolin-mediated endocytosis →	+0.210	+1.434	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,153 associations by consensus.

Regulation of Golgi inheritance by PXMP4 expression — UPPER_AERODIGESTIVE_TRACT

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