PXMP2

Across TCGA patient cohorts, PXMP2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,504 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PXMP2-associated genes across cancer lineages are RFC5, KMT5A, and CIT. Each is linked with PXMP2 in more than 4 cancer types. Because this analysis shows association rather than direction, both PXMP2-to-partner and partner-to-PXMP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PXMP2 versus RFC5 in LSCC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PXMP2→partner) and Y-score (partner→PXMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RFC5 →	+0.603	+0.331	<.001	<.001	3	5
LUAD	KMT5A →	+0.466	+0.401	<.001	.003	3	4
LUAD	CIT →	+0.938	+0.519	.002	<.001	3	4
PDAC	CYC1 →	+0.613	+0.682	.004	<.001	3	4
PDAC	SUV39H1 →	+0.434	+0.696	.001	<.001	3	4
PDAC	ERI3 →	+0.467	+0.610	.003	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,504 associations by consensus.

PXMP2 vs RFC5 — LSCC

Explore this scatter interactively →