PXMP2

Across TCGA cell cohorts, PXMP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,948 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PXMP2-associated GO terms across cancer lineages are DNA strand elongation involved in DNA replication, Regulation of sister chromatid segregation, and Nuclear division. Each is linked with PXMP2 in more than 16 cancer types. Because this analysis shows association rather than direction, both PXMP2-to-partner and partner-to-PXMP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA strand elongation involved in DNA replication grouped by PXMP2-low versus PXMP2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PXMP2→partner) and Y-score (partner→PXMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA strand elongation involved in DNA replication →	+0.199	+1.107	.004	.003	3	17
BREAST	Regulation of sister chromatid segregation →	+0.112	+0.892	<.001	.008	2	16
SOFT_TISSUE	Nuclear division →	+0.080	+1.420	<.001	<.001	3	15
BLOOD_Lymphoma	Regulation of chromosome segregation →	+0.109	+1.447	<.001	<.001	3	15
SOFT_TISSUE	Regulation of mitotic sister chromatid separation →	+0.147	+1.530	<.001	<.001	3	14
SOFT_TISSUE	Regulation of chromosome separation →	+0.152	+1.348	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,948 associations by consensus.

DNA strand elongation involved in DNA replication by PXMP2 expression — BONE

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