PXK

Across TCGA patient cohorts, PXK RNA expression is significantly associated with the protein abundance of many other proteins, with 19,023 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PXK-associated proteins across cancer lineages are CNRIP1, GAS7, and TTI1. Each is linked with PXK in more than 5 cancer types. Because this analysis shows association rather than direction, both PXK-to-partner and partner-to-PXK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PXK versus CNRIP1 in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PXK→partner) and Y-score (partner→PXK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CNRIP1 →	+0.616	+0.648	<.001	<.001	3	6
BRCA	GAS7 →	+0.538	+0.677	<.001	<.001	3	6
PDAC	TTI1 →	-0.255	-0.260	.003	.004	3	6
BRCA	RPS3 →	-0.245	-0.620	<.001	<.001	3	5
GBM	SEPTIN4 →	+0.576	+0.427	<.001	<.001	3	5
BRCA	SGCD →	+0.625	+0.612	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,023 associations by consensus.

PXK vs CNRIP1 — BRCA

Explore this scatter interactively →