PXK

Across TCGA patient cohorts, PXK protein abundance is significantly associated with the RNA expression of many other genes, with 15,385 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PXK-associated genes across cancer lineages are ASPA, ZEB2, and MILR1. Each is linked with PXK in more than 5 cancer types. Because this analysis shows association rather than direction, both PXK-to-partner and partner-to-PXK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PXK versus ASPA in GBM, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PXK→partner) and Y-score (partner→PXK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ASPA →	+1.042	+0.336	.004	<.001	3	6
BRCA	ZEB2 →	+0.789	+0.252	<.001	<.001	3	6
OV	MILR1 →	+1.069	+0.458	.003	.004	3	6
HNSC	CXCL12 →	+1.104	+0.192	<.001	<.001	3	6
GBM	ATP8B4 →	+0.976	+0.352	<.001	<.001	3	6
HNSC	FLI1 →	+0.748	+0.247	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,385 associations by consensus.

PXK vs ASPA — GBM

Explore this scatter interactively →