PWWP3A

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PWWP3A RNA expression is significantly associated with the protein abundance of many other proteins, with 13,952 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PWWP3A-associated proteins across cancer lineages are SEC23B, LMNB2, and ISG20. Each is linked with PWWP3A in more than 5 cancer types. Because this analysis shows association rather than direction, both PWWP3A-to-partner and partner-to-PWWP3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PWWP3A versus SEC23B in OV, with a Pearson correlation of -0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PWWP3A→partner) and Y-score (partner→PWWP3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVSEC23B →-0.316-0.669.001<.00136
OVLMNB2 →+0.436+0.823<.001<.00136
HNSCISG20 →-0.684-0.431<.001<.00135
GBMKHSRP →+0.249+0.455<.001<.00135
OVGNA11 →+0.351+0.832<.001<.00135
LUADTNPO2 →+0.298+0.393<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,952 associations by consensus.

PWWP3A vs SEC23B — OV

Per-sample scatter of PWWP3A vs SEC23B in OV (Pearson r = -0.31).

Explore this scatter interactively →

Exploration