PWWP3A

Across TCGA patient cohorts, PWWP3A protein abundance is significantly associated with the RNA expression of many other genes, with 7,354 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PWWP3A-associated genes across cancer lineages are MASP1, TUBB1, and TNR. Each is linked with PWWP3A in more than 2 cancer types. Because this analysis shows association rather than direction, both PWWP3A-to-partner and partner-to-PWWP3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PWWP3A versus MASP1 in GBM, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PWWP3A→partner) and Y-score (partner→PWWP3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MASP1 →	+0.954	+0.183	<.001	<.001	3	3
GBM	TUBB1 →	+0.439	+0.288	.001	<.001	3	2
LSCC	TNR →	+0.172	+0.247	.005	<.001	3	2
GBM	GCM2 →	+0.443	+0.204	<.001	<.001	3	2
GBM	SKOR1 →	+0.343	+0.207	<.001	<.001	3	2
UCEC	ADAMTSL4-AS1 →	+0.518	+0.194	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,354 associations by consensus.

PWWP3A vs MASP1 — GBM

Explore this scatter interactively →