PWAR5

Across TCGA patient cohorts, PWAR5 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,170 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible PWAR5-associated GO terms across cancer lineages are Telomere maintenance via telomere lengthening, Transport along microtubule, and Endosomal transport. Each is linked with PWAR5 in more than 32 cancer types. Because this analysis shows association rather than direction, both PWAR5-to-partner and partner-to-PWAR5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere maintenance via telomere lengthening grouped by PWAR5-low versus PWAR5-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PWAR5→partner) and Y-score (partner→PWAR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Telomere maintenance via telomere lengthening →	+0.063	+0.537	<.001	<.001	3	33
UCS	Transport along microtubule →	+0.043	+0.896	<.001	<.001	3	33
STAD	Endosomal transport →	+0.054	+0.601	<.001	<.001	3	33
ESCA	Protein polyubiquitination →	+0.059	+0.858	<.001	<.001	3	33
ESCA	Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.070	+0.915	<.001	<.001	3	33
ESCA	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.081	+0.967	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,170 associations by consensus.

Telomere maintenance via telomere lengthening by PWAR5 expression — DLBC

Explore this box plot interactively →