PWAR1

Across TCGA patient cohorts, PWAR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,157 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PWAR1-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, and DNA-templated transcription elongation. Each is linked with PWAR1 in more than 30 cancer types. Because this analysis shows association rather than direction, both PWAR1-to-partner and partner-to-PWAR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by PWAR1-low versus PWAR1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PWAR1→partner) and Y-score (partner→PWAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Epigenetic regulation of gene expression →	+0.066	+0.060	<.001	<.001	3	31
DLBC	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.078	+0.104	<.001	<.001	3	30
STAD	DNA-templated transcription elongation →	+0.072	+0.064	<.001	<.001	3	30
STAD	Peptidyl-lysine modification →	+0.065	+0.086	<.001	<.001	3	30
DLBC	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.078	+0.127	.001	<.001	3	29
STAD	Nuclear export →	+0.074	+0.066	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,157 associations by consensus.

Epigenetic regulation of gene expression by PWAR1 expression — STAD

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