PVT1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PVT1 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PVT1-associated genes across cancer lineages are Neutrophils. Each is linked with PVT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PVT1-to-partner and partner-to-PVT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neutrophils grouped by PVT1-low versus PVT1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PVT1→partner) and Y-score (partner→PVT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNeutrophils →+0.024+2.751.001.04431
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Neutrophils by PVT1 expression — UCEC

Box plot of Neutrophils in PVT1-low vs PVT1-high samples in UCEC.

Explore this box plot interactively →

Exploration