Across TCGA patient cohorts, PVALEF RNA expression is significantly associated with the protein abundance of many other proteins, with 12,295 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PVALEF-associated proteins across cancer lineages are TTC7A_S647, TCEAL1, and MSN. Each is linked with PVALEF in more than 3 cancer types. Because this analysis shows association rather than direction, both PVALEF-to-partner and partner-to-PVALEF results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PVALEF→partner) and Y-score (partner→PVALEF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TTC7A_S647 →	-0.566	-0.361	<.001	<.001	3	4
BRCA	TCEAL1 →	+0.435	+0.129	.001	.001	3	4
GBM	MSN →	-0.519	-0.304	<.001	<.001	3	4
GBM	ITPRID2_S767 →	-0.539	-0.377	<.001	<.001	3	4
GBM	ARPC1B →	-0.496	-0.320	.001	<.001	3	4
BRCA	ACTR3 →	-0.195	-0.221	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,295 associations by consensus.

Exploration

PVALEF survival (RNA) · tumor vs normal (RNA) · all PVALEF data types