PVALB

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PVALB RNA expression is significantly associated with the protein abundance of many other proteins, with 15,097 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PVALB-associated proteins across cancer lineages are DTNA, MAP1A_S2022, and DDX52. Each is linked with PVALB in more than 3 cancer types. Because this analysis shows association rather than direction, both PVALB-to-partner and partner-to-PVALB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PVALB versus DTNA in HNSC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PVALB→partner) and Y-score (partner→PVALB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCDTNA →+0.913+0.397<.001.00134
LSCCMAP1A_S2022 →+1.011+0.821<.001.00334
COADDDX52 →-0.225-0.157.007.00534
GBMRPL3 →-0.403-1.133<.001<.00133
GBMRPL7 →-0.269-0.561.001.00433
LUADS100A9_T113 →-0.974-0.304<.001.00333
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,097 associations by consensus.

PVALB vs DTNA — HNSC

Per-sample scatter of PVALB vs DTNA in HNSC (Pearson r = 0.35).

Explore this scatter interactively →

Exploration