PVALB

Across TCGA cell cohorts, PVALB RNA expression is significantly associated with the go_rna of many other GO terms, with 886 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible PVALB-associated GO terms across cancer lineages are Cell adhesion mediated by integrin, Tubulin deacetylation, and Positive regulation of mesenchymal cell proliferation. Each is linked with PVALB in more than 4 cancer types. Because this analysis shows association rather than direction, both PVALB-to-partner and partner-to-PVALB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell adhesion mediated by integrin grouped by PVALB-low versus PVALB-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PVALB→partner) and Y-score (partner→PVALB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Cell adhesion mediated by integrin →	-0.173	-1.777	<.001	.007	3	5
SOFT_TISSUE	Tubulin deacetylation →	+0.101	+1.520	<.001	.005	3	5
BREAST	Positive regulation of mesenchymal cell proliferation →	-0.196	-1.696	<.001	.007	3	4
LARGE_INTESTINE	Purine ribonucleoside monophosphate biosynthetic process →	-0.123	-0.076	<.001	.008	3	3
OVARY	Gland morphogenesis →	-0.108	-0.124	.008	.001	3	3
BREAST	Gastrulation →	-0.098	-1.778	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 886 associations by consensus.

Cell adhesion mediated by integrin by PVALB expression — BREAST

Explore this box plot interactively →