PUSL1

Across TCGA cell cohorts, PUSL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,440 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PUSL1-associated GO terms across cancer lineages are Pseudouridine synthesis, rRNA pseudouridine synthesis, and Regulation of DNA stability. Each is linked with PUSL1 in more than 12 cancer types. Because this analysis shows association rather than direction, both PUSL1-to-partner and partner-to-PUSL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pseudouridine synthesis grouped by PUSL1-low versus PUSL1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PUSL1→partner) and Y-score (partner→PUSL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Pseudouridine synthesis →	+0.119	+1.406	<.001	.001	3	13
BONE	rRNA pseudouridine synthesis →	+0.135	+1.086	<.001	<.001	3	13
BONE	Regulation of DNA stability →	+0.120	+0.943	<.001	.001	3	12
SKIN	tRNA pseudouridine synthesis →	+0.094	+1.162	<.001	<.001	3	12
BONE	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.183	+1.084	<.001	<.001	3	11
BONE	Enzyme-directed rRNA pseudouridine synthesis →	+0.092	+0.795	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,440 associations by consensus.

Pseudouridine synthesis by PUSL1 expression — OESOPHAGUS

Explore this box plot interactively →