PUSL1

Across TCGA cell cohorts, PUSL1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PUSL1-associated genes across cancer lineages are CLEC9A and MEIKIN. Each is linked with PUSL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PUSL1-to-partner and partner-to-PUSL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLEC9A grouped by PUSL1-low versus PUSL1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PUSL1→partner) and Y-score (partner→PUSL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CLEC9A →	+0.023	+4.977	<.001	.007	3	1
BREAST	MEIKIN →	+0.099	+5.169	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CLEC9A by PUSL1 expression — LARGE_INTESTINE

Explore this box plot interactively →