PUS7

Across TCGA cell cohorts, PUS7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,464 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PUS7-associated GO terms across cancer lineages are DNA replication initiation, DNA-templated transcription termination, and Mitochondrial RNA metabolic process. Each is linked with PUS7 in more than 16 cancer types. Because this analysis shows association rather than direction, both PUS7-to-partner and partner-to-PUS7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by PUS7-low versus PUS7-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PUS7→partner) and Y-score (partner→PUS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DNA replication initiation →	+0.183	+1.053	<.001	<.001	3	17
SOFT_TISSUE	DNA-templated transcription termination →	+0.120	+1.185	<.001	<.001	3	17
BONE	Mitochondrial RNA metabolic process →	+0.100	+1.134	.005	.004	3	17
PANCREAS	Regulation of mesoderm development →	+1.162	+1.186	<.001	<.001	3	17
LUNG_SCLC	XMP metabolic process →	+0.184	+0.826	<.001	<.001	3	17
LUNG_SCLC	XMP biosynthetic process →	+0.184	+0.826	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,464 associations by consensus.

DNA replication initiation by PUS7 expression — SOFT_TISSUE

Explore this box plot interactively →