PURG

Across TCGA patient cohorts, PURG protein abundance is significantly associated with the RNA expression of many other genes, with 5,258 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PURG-associated genes across cancer lineages are MIR147A, UPK3A, and IL2RB. Each is linked with PURG in more than 1 cancer types. Because this analysis shows association rather than direction, both PURG-to-partner and partner-to-PURG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PURG versus MIR147A in UCEC, with a Pearson correlation of 0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PURG→partner) and Y-score (partner→PURG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR147A →	+1.966	+1.737	.001	.001	3	2
UCEC	UPK3A →	-0.335	-2.050	.007	.004	3	1
UCEC	IL2RB →	+1.256	+1.835	.007	.001	3	1
UCEC	FERMT1 →	-1.969	-1.964	<.001	.001	3	1
UCEC	SLC7A5 →	+1.612	+2.130	.004	.002	3	1
UCEC	DNAH11 →	+2.830	+1.657	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,258 associations by consensus.

PURG vs MIR147A — UCEC

Explore this scatter interactively →