PURG

Across TCGA cell cohorts, PURG RNA expression is significantly associated with the go_rna of many other GO terms, with 4,464 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PURG-associated GO terms across cancer lineages are Microtubule-based transport, Renal vesicle formation, and Metanephric renal vesicle formation. Each is linked with PURG in more than 11 cancer types. Because this analysis shows association rather than direction, both PURG-to-partner and partner-to-PURG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule-based transport grouped by PURG-low versus PURG-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PURG→partner) and Y-score (partner→PURG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Microtubule-based transport →	+0.059	+1.189	<.001	<.001	3	12
LUNG_SCLC	Renal vesicle formation →	+0.811	+0.884	.004	.007	3	11
LUNG_SCLC	Metanephric renal vesicle formation →	+0.811	+0.884	.004	.007	3	11
LUNG_SCLC	Transport along microtubule →	+0.062	+1.224	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Cytoskeleton-dependent intracellular transport →	+0.054	+0.852	<.001	.009	3	9
BONE	DNA-templated transcription initiation →	+0.080	+1.275	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,464 associations by consensus.

Microtubule-based transport by PURG expression — LUNG_SCLC

Explore this box plot interactively →