PURB

Across TCGA patient cohorts, PURB RNA expression is significantly associated with the protein abundance of many other proteins, with 12,705 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PURB-associated proteins across cancer lineages are FOXK1_S213, FOXK1, and NUDCD3. Each is linked with PURB in more than 6 cancer types. Because this analysis shows association rather than direction, both PURB-to-partner and partner-to-PURB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PURB versus FOXK1_S213 in PDAC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PURB→partner) and Y-score (partner→PURB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	FOXK1_S213 →	+0.492	+0.326	<.001	.001	3	7
LUAD	FOXK1 →	+0.352	+0.582	<.001	<.001	3	6
BRCA	NUDCD3 →	+0.329	+0.522	<.001	<.001	3	6
LSCC	XPO1 →	+0.191	+0.421	<.001	<.001	3	5
LSCC	CSE1L →	+0.298	+0.406	.002	.002	3	5
LSCC	GTF3C1 →	+0.308	+0.532	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,705 associations by consensus.

PURB vs FOXK1_S213 — PDAC

Explore this scatter interactively →