PUF60

Across TCGA cell cohorts, PUF60 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,977 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PUF60-associated GO terms across cancer lineages are Chromosome condensation, Maintenance of sister chromatid cohesion, and Maintenance of mitotic sister chromatid cohesion. Each is linked with PUF60 in more than 15 cancer types. Because this analysis shows association rather than direction, both PUF60-to-partner and partner-to-PUF60 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chromosome condensation grouped by PUF60-low versus PUF60-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PUF60→partner) and Y-score (partner→PUF60) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Chromosome condensation →	+0.155	+0.868	.003	.007	3	16
BONE	Maintenance of sister chromatid cohesion →	+0.125	+0.930	.001	.003	3	15
BONE	Maintenance of mitotic sister chromatid cohesion →	+0.125	+0.930	.001	.003	3	15
BLOOD_Myeloma	Nucleosome disassembly →	+0.153	+1.038	.001	.002	2	16
PANCREAS	Positive regulation of cell cycle phase transition →	+0.085	+0.725	<.001	.002	3	15
BONE	DNA-templated DNA replication →	+0.116	+1.016	.005	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,977 associations by consensus.

Chromosome condensation by PUF60 expression — BONE

Explore this box plot interactively →